Talk:Orotic acid
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Untitled
[edit]not enough info. mention:
1) orotic acid is an intermediate in pyrimidine synthesis (C, T)
2) multi-organ tumour promoter
74.111.2.51 02:10, 11 December 2006 (UTC) Prof. Larry Moran, PhD. University of Toronto, Department of Biochemistry
Wrong Lemma
[edit]It's not pyrimidinecarboxylic acid, the systematic name is 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid or uracil-6-carboxylic acid, but orotic acid is more common. -- 217.224.70.151 13:09, 26 July 2006 (UTC)
Vitamin?
[edit]The article states that "...it is not a vitamin, but is instead manufactured in the body by intestinal flora." By that definition, vitamin K wouldn't be a vitamin. --ἀνυπόδητος (talk) 11:39, 31 July 2009 (UTC)
- Vitamin K is available via microbial action, but some humans still need supplements. Bearian (talk) 16:11, 2 October 2014 (UTC)
Orotic Acid Mutagen?
[edit]There is no proper citation of the rather serious claim that Orotic Acid, a necessary nutrient for humans to live, is a mutagenic compound. A google search pulled up nothing except a few abstracts about 5-Fluoro-Orotic Acid, a different compound altogether. — Preceding unsigned comment added by 65.190.21.85 (talk) 00:23, 26 December 2013 (UTC)
A Google search on 12/27/2014 turned up a materials safety data sheet for orotic acid, anhydrous (1,2,3,6-Tetrahydro-2,6-dioxo-4- pyrimidinecarboxylic Acid; 6-Uracilcarboxylic Acid) from ScienceLab.com that states: "Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/ or yeast." [1] Also found this substance listed as having an RTECS class of Mutagen. [2]
References
Tricreatine orotate
[edit]This article has been proposed for deletion. However, otherwise non-notable salts of an acid should be merged into the parent article when feasible. Bearian (talk) 16:12, 2 October 2014 (UTC)
Done. The tricreatine orotate article was at best poorly sourced, but I claim no expertise in this area. Hopefully someone with a greater knowledge of chemistry can provide a decent source for the merged content. Euryalus (talk) 12:45, 11 October 2014 (UTC)
Pronunciation
[edit]Because of the unfortunate name of B¹³, I propose the correct pronunciation be added to the article to prevent confusion. 68.185.117.66 (talk) 15:04, 6 November 2022 (UTC)
- Well it is an acid with a rather funny name, but the correct way to say it is Or-ot-ic acid. I have no idea of how to use the IPA system.If someone can transscribe the name it would be a great help. Cadmium (talk) 10:34, 7 February 2023 (UTC)