Talk:Kaguya (mouse)

Primary Kaguya Article

Not that this isn't a fascinating article, but this is the first article that pops up when you search for Kaguya on wikipedia. Wouldn't it make more sense for the primary article to be related to the original Japanese legend, and for this page to be moved to an appropriate alternate location? 68.148.224.47 08:38, 22 June 2007 (UTC)

Surety

I am unsure of the veracity of these statements:

This is not a cloned animal because cells from two individuals are used

and

the process used starts with genetically modified mice

First, as far as I have read, there is nothing that says that the cells came from different individuals, only that they were different cells, one taken immaturely and the other taken later. Nonetheless, the processes involved in meiosis would still ensure that it was not a clone.

Second, the mice themselves are not genetically modified, only the eggs — as far as I have read.

-moogle 05:15, 22 Apr 2005 (UTC)

Disambiguation here?

Modified eggs?

I have read the original paper published in Nature magazine. As far as I remember 2 individuals were used, one was mutant and other one normal. So they took premature egg from young mutant and mature egg from normal adult mouse. I am not sure how do you mean eggs can be mofified (dna of eggs)? They created modified animal that produced modified eggs...

If they used 2 normal animals placenta wouldnt develop properly because of paternal and maternal imprints. So I wondered if someone can tell me, is it theoretically possible to create normal individual by gene therapy which means silencing matriline and amplifying paternally expressed genes without changing their DNA, and can those offspring be fertile?

Thanks

Fair use rationale for Image:Mouse 180.jpg

Image:Mouse 180.jpg is being used on this article. I notice the image page specifies that the image is being used under fair use but there is no explanation or rationale as to why its use in this Wikipedia article constitutes fair use. In addition to the boilerplate fair use template, you must also write out on the image description page a specific explanation or rationale for why using this image in each article is consistent with fair use.

Please go to the image description page and edit it to include a fair use rationale. Using one of the templates at Wikipedia:Fair use rationale guideline is an easy way to insure that your image is in compliance with Wikipedia policy, but remember that you must complete the template. Do not simply insert a blank template on an image page.

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BetacommandBot (talk) 06:57, 1 January 2008 (UTC)

Changing the Page Name

Hello,

We are planning to expand and improve this page. After a quick look at recent literature, it does not seem like Kaguya mouse is being actively studied . It certainly played a crucial role in our understanding of developmental genetics, but it is not a model.

Additionally, as another commenter mentioned below, it is highly unlikely that a person searching for "Kaguya" would be actually looking for the Kaguya mouse.

To improve this and make this more relevant to interested readers, we are considering changing the name of the page from "Kaguya (mouse)" to "Gynogenetic Mouse." We will maintain Kaguya mouse as a major subsection of this page due to its important contribution to the topic. This will also allow us to update the topic with more recent advances.

Please let me know if you have any suggestions or objections. I will wait 72hrs and after that I may go ahead with my proposed changes at any time. I will make sure to share a detailed version of these changes here before committing them.

Blast Me Pls (talk) 01:55, 19 September 2024 (UTC)